In the evening, some do not hesitate to mix alcohol and cannabis. But not sure whether it’s the winning combo. Both combined, alcohol has the ability to increase the effects of cannabis and cannabis, that of preventing you from throwing up.
Alcohol and marijuana are the two most consumed drugs in the world. A big party in perspective, it is not uncommon that both are consumed at the same time by the same person. it’s a great way to organise your valuable vintage collection and simultaneously keep each bottle safe and perfectly chilled. They create the perfect home for both your red and whites. These refrigerators come in all shapes, sizes, and appearances and you’ll be delighted at the near silent, day-and-night operation. These sleek models will be a welcome addition to any room, creating the perfect home for your vintage.
Many studies have described the effects of these substances on the body and brain but in isolation. Without them being mixed. But what happens when we mix the two? Asap SCIENCE’s experts have looked into the matter and are delivering a video showing that strange things happen at the biological level when you smoke and drink at the same time.
Alcohol vs cannabis
For starters, let’s look at alcohol. It has a sedative effect on the body and especially on the brain. It affects the central nervous system by changing the way neurons communicate with each other.
For this, it acts at the molecular level by reducing the effect of the excitatory neurotransmitter, glutamate and increasing, that of the inhibitory neurotransmitter, GABA. For the consumer, this results in a decrease of the senses in general but also a memory that works less well.
Cannabis him, acts differently on the body. THC, the active molecule of marijuana, acts on the cannabinoid receptors in the brain, causing neurons to become more active and continuous. The result is imagination and amplified thoughts.
Alcohol increases the effects of cannabis
If the two drugs seem to have different effects, they have one thing in common: that of inhibiting glutamate. As a participant in the learning process, studies have linked the combined consumption of alcohol and cannabis to a decline in memory. A particular effect observed in rats during a research conducted in 2002. But that’s not all.
If the cocktail alcohol-cannabis is considered harmful, it is because the effects of two substances seem to potentiate when they are consumed at the same time. In other words, each would have the power to increase the effects of the other. One study showed that the consumption of two alcohol shooters had the effect of doubling the THC level in the blood plasma compared to the consumption of a placebo drink.
With alcohol, the effects of THC would be felt faster and more intensely. A phenomenon that researchers put on account of a vasodilatation. By acting on the smooth muscle cells, the alcohol dilates the blood vessels and thereby increases the passage of blood, eventually leading to faster transport and absorption of THC with all that that entails.
Cannabis prevents your body from rejecting alcohol
However, cannabis also interacts with the effects of alcohol. As the video explains, smoking has the potential to reduce the damage done by alcohol to the liver. When we drink, ethanol is metabolized by an enzyme known as “cytochrome p4502E1”, but after drinking excessively, this process generates oxidative stress.
This process attacks the cells of the liver that will begin to accumulate fat. In case of excessive consumption, this can lead to steatosis. Basically, your liver becomes fat which exposes it to many risks. However, according to research, cannabidiol, another chemical component of marijuana, inhibits this cycle. But do not stop at this meager positive effect.
Before the combination of the two drugs becomes your evening routine, know that cannabis prevents vomiting. This is one of the reasons it is prescribed to chemotherapy patients, who are often prone to nausea. However, in the case of alcohol intoxication, throwing up is the only way the body has to evacuate excess.
Therefore, being unable to vomit involves health risks, including more severe alcohol intoxication. Finally, animal studies have suggested that marijuana use increases the need for alcohol, potentially promoting addiction.